Cannabidiol alleviates neurological deficits after traumatic brain injury by improving intracranial lymphatic drainage
AbstractTraumatic brain injury (TBI)—a severe clinical problem—is compounded by a lack of effective treatments and impeded intracranial metabolic waste clearance. The glymphatic system and meningeal
Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis
Abstract Cannabis sativa is a multipurpose plant that has been used in medicine for centuries. Recently, considerable research has focused on the bioactive compounds of this
CBD could reverse opioid overdoses
FOR IMMEDIATE RELEASE INDIANAPOLIS, March 28, 2023 — There’s been a recent push in the U.S. to make naloxone — a fast-acting opioid antidote —
Cannabidiol goes nuclear: The role of PPARγ
Abstract Background Cannabidiol (CBD) is one of the main phytocannabinoids found in Cannabis sativa. In contrast to Δ9-tetrahydrocannabinol, it has a low affinity for cannabinoid receptors CB1
The Effect of Cannabis Plant Extracts on Head and Neck Squamous Cell Carcinoma and the Quest for Cannabis-Based Personalized Therapy
Simple Summary The survival rate of head and neck cancer has only improved slightly over the last quarter century, raising the need for novel therapies
Cannabis Dosing Strategy: A Detailed Analysis with host Shango Los
CBD & Colorectal Cancer
A collection and occasional review of research on the effects of CBD on Colorectal Cancer. Since CBD has been found to down regulate Id-1 we
CBD & Cervical Cancer
Pre-clinical evidence A collection and occasional review of research on the effects of CBD on Cervical Cancer. Since CBD has been found to down regulate
CBD & Gastric Cancer
Here we take a look at the available research and anecdotal evidence supporting the use of CBD against gastric cancer. Pre-clinical evidence Two in vitro
What is CBDV?
What is CBDV? Learn all about this newly available phytocannabinoid…what it is, who might benefit from its medicinal properties and more… After witnessing the incredible
Cannabis for Autism
Whole Plant Access for Autism (WPA4A) is a 501(c)(3) nonprofit that works to educate families all over the world about the possible benefits of cannabis
Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial–mesenchymal transition through the Wnt/β-catenin signaling pathway
Abstract Colorectal cancer (CRC) is the leading cause of cancer deaths worldwide, wherein distant metastasis is the main reason for death. The non-psychoactive phytocannabinoid cannabidiol (CBD)
Cannabinoid Hyperemesis Syndrome
There are many myths and misconceptions about Cannabinoid Hyperemesis Syndrome. In this video, I share the latest scientific understanding, including signs and symptoms, potential mechanisms
What is CBG?
Curious about CBG? Here is the latest research and clinical information about cannabigerol, an amazing medicinal phytocannabinoid from the cannabis plant. After witnessing the incredible
Cannabidiol exerts anti-proliferative activity via a cannabinoid receptor 2-dependent mechanism in human colorectal cancer cells
Abstract Colorectal cancer is the third leading cause of cancer incidence and mortality in the United States. Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis
Endogenous Anandamide Like Compounds – Raphael Mechoulam, PhD
Raphael Mechoulam, PhD presents “Endogenous Anandamide Like Compounds” at CannMed 2022.
Enhancement of Conventional Treatment of Cervical Cancer with CBD
Enhancement of Conventional and Photodynamic Therapy for Treatment of Cervical Cancer with Cannabidiol Abstract Cervical cancer (CC) is the fourth most diagnosed cancer in women
Cannabidiol on the Path from the Lab to the Cancer Patient: Opportunities and Challenges
Abstract Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent. CBD suppresses the development of cancer in
Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment
Abstract Introduction: Glioblastoma (GBM) is the most common invasive brain tumor composed of diverse cell types with poor prognosis. The highly complex tumor microenvironment (TME) and
Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes to disease progression, recurrence, and mortality. The
CNN’s Dr. Sanjay Gupta on Reversing His Medical Cannabis Stance
Cannabidiol suppresses 3-dimensional ovarian cancer growth and may enhance potency of classic and epigenetic therapies
Over an extended kinetic, high and medium concentrations of one time CBD (CBDH) tended to stunt spheroid growth in comparison to control, (686% and over
Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins
Abstract Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of the prometastatic gene inhibitor of DNA binding
Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
Abstract The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD), a compound produced by the cannabis plant,
Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma
Abstract Cannabidiol (CBD) has anti-tumorigenic activity. However, the anti-cancer effect of CBD on head and neck squamous cell carcinoma (HNSCC) remains unclear. The cytotoxicity of
CBD as a Promising Anti-Cancer Drug
Abstract Recently, cannabinoids, such as cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array
Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticles
In this work, we evaluated, for the first time, the antitumor effect of cannabidiol (CBD) as monotherapy and in combination with conventional chemotherapeutics in ovarian
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
Abstract Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The non-psychoactive phytocannabinoid cannabidiol (CBD) has been shown
The potential of cannabidiol in the COVID-19 pandemic
Identifying candidate drugs effective in the new coronavirus disease 2019 (Covid‐19) is crucial, pending a vaccine against SARS‐CoV2. We suggest the hypothesis that Cannabidiol (CBD),
Dr. David Allen Explains Medical Cannabis
Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1
Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
Id-1: Regulator of EGFR and VEGF and potential target for colorectal cancer therapy
Expression of the inhibitor of DNA-binding (ID)-1 protein as an angiogenic mediator in tumour advancement of uterine cervical cancers
Overexpression of Id-1 protein is a marker in colorectal cancer progression
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells
Level of Id-1 Protein Expression Correlates with Poor Differentiation, Enhanced Malignant Potential, and More Aggressive Clinical Behavior of Epithelial Ovarian Tumors
Overexpression of Id-1 Protein Is a Marker for Unfavorable Prognosis in Early-Stage Cervical Cancer
Differentiation and reversal of malignant changes in colon cancer through PPARγ
Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish
anandamide autism bonni goldstein brain cancer breast cancer cancer cannabidiol Cannabinoid Hyperemesis Syndrome cannabinoids cbc cbd cbdv cbg cervical cancer cervical cancer Id-1 colon cancer colorectal cancer colorectal cancer id-1 covid ecs endocannabinoid system ependymoma epilepsy gastric cancer GDF15 glioblastoma glioma head and neck cancer Id-1 JNK1 JNK2 leukemia lung cancer lymphatic drainage opioids ovarian cancer ovarian cancer Id-1 pancreatic cancer physiological effects PPARγ prostate cancer raphael mechoulam self-renewal traumatic brain injury TRPV2