Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment
Abstract Introduction: Glioblastoma (GBM) is the most common invasive brain tumor composed of diverse cell types with poor prognosis….
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Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
Abstract Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The…
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ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma
Abstract Glioblastoma is the most common primary brain tumor in adults. While the introduction of temozolomide chemotherapy has…
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Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Abstract Glioblastoma multiforme (GBM) is the most common and aggressive form of primary malignant brain tumor in adults,…
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Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways
Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The challenging problem in cancer…
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Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
Abstract The aggressive behavior of Glioblastoma multiforme (GBM) is mainly due to high invasiveness and proliferation rate as…
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The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells
Abstract Recently, we have shown that the non-psychoactive cannabinoid compound cannabidiol (CBD) induces apoptosis of glioma cells in vitro and…