Cannabidiol alleviates neurological deficits after traumatic brain injury by improving intracranial lymphatic drainage
AbstractTraumatic brain injury (TBI)—a severe clinical problem—is compounded by a lack of effective treatments and impeded intracranial metabolic waste clearance. The glymphatic system and meningeal
Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis
Abstract Cannabis sativa is a multipurpose plant that has been used in medicine for centuries. Recently, considerable research has focused on the bioactive compounds of this
CBD could reverse opioid overdoses
FOR IMMEDIATE RELEASE INDIANAPOLIS, March 28, 2023 — There’s been a recent push in the U.S. to make naloxone — a fast-acting opioid antidote —
Cannabidiol goes nuclear: The role of PPARγ
Abstract Background Cannabidiol (CBD) is one of the main phytocannabinoids found in Cannabis sativa. In contrast to Δ9-tetrahydrocannabinol, it has a low affinity for cannabinoid receptors CB1
The Effect of Cannabis Plant Extracts on Head and Neck Squamous Cell Carcinoma and the Quest for Cannabis-Based Personalized Therapy
Simple Summary The survival rate of head and neck cancer has only improved slightly over the last quarter century, raising the need for novel therapies
Cannabis Dosing Strategy: A Detailed Analysis with host Shango Los
CBD & Colorectal Cancer
A collection and occasional review of research on the effects of CBD on Colorectal Cancer. Since CBD has been found to down regulate Id-1 we
CBD & Cervical Cancer
Pre-clinical evidence A collection and occasional review of research on the effects of CBD on Cervical Cancer. Since CBD has been found to down regulate
CBD & Gastric Cancer
Here we take a look at the available research and anecdotal evidence supporting the use of CBD against gastric cancer. Pre-clinical evidence Two in vitro
What is CBDV?
What is CBDV? Learn all about this newly available phytocannabinoid…what it is, who might benefit from its medicinal properties and more… After witnessing the incredible
Cannabis for Autism
Whole Plant Access for Autism (WPA4A) is a 501(c)(3) nonprofit that works to educate families all over the world about the possible benefits of cannabis
Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial–mesenchymal transition through the Wnt/β-catenin signaling pathway
Abstract Colorectal cancer (CRC) is the leading cause of cancer deaths worldwide, wherein distant metastasis is the main reason for death. The non-psychoactive phytocannabinoid cannabidiol (CBD)
Cannabinoid Hyperemesis Syndrome
There are many myths and misconceptions about Cannabinoid Hyperemesis Syndrome. In this video, I share the latest scientific understanding, including signs and symptoms, potential mechanisms
What is CBG?
Curious about CBG? Here is the latest research and clinical information about cannabigerol, an amazing medicinal phytocannabinoid from the cannabis plant. After witnessing the incredible
Cannabidiol exerts anti-proliferative activity via a cannabinoid receptor 2-dependent mechanism in human colorectal cancer cells
Abstract Colorectal cancer is the third leading cause of cancer incidence and mortality in the United States. Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis
Endogenous Anandamide Like Compounds – Raphael Mechoulam, PhD
Raphael Mechoulam, PhD presents “Endogenous Anandamide Like Compounds” at CannMed 2022.
Enhancement of Conventional Treatment of Cervical Cancer with CBD
Enhancement of Conventional and Photodynamic Therapy for Treatment of Cervical Cancer with Cannabidiol Abstract Cervical cancer (CC) is the fourth most diagnosed cancer in women
Cannabidiol on the Path from the Lab to the Cancer Patient: Opportunities and Challenges
Abstract Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent. CBD suppresses the development of cancer in
Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment
Abstract Introduction: Glioblastoma (GBM) is the most common invasive brain tumor composed of diverse cell types with poor prognosis. The highly complex tumor microenvironment (TME) and
Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes to disease progression, recurrence, and mortality. The
CNN’s Dr. Sanjay Gupta on Reversing His Medical Cannabis Stance
Cannabidiol suppresses 3-dimensional ovarian cancer growth and may enhance potency of classic and epigenetic therapies
Over an extended kinetic, high and medium concentrations of one time CBD (CBDH) tended to stunt spheroid growth in comparison to control, (686% and over
Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins
Abstract Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of the prometastatic gene inhibitor of DNA binding
Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
Abstract The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD), a compound produced by the cannabis plant,
Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma
Abstract Cannabidiol (CBD) has anti-tumorigenic activity. However, the anti-cancer effect of CBD on head and neck squamous cell carcinoma (HNSCC) remains unclear. The cytotoxicity of
CBD as a Promising Anti-Cancer Drug
Abstract Recently, cannabinoids, such as cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array
Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticles
In this work, we evaluated, for the first time, the antitumor effect of cannabidiol (CBD) as monotherapy and in combination with conventional chemotherapeutics in ovarian
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
Abstract Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The non-psychoactive phytocannabinoid cannabidiol (CBD) has been shown
The potential of cannabidiol in the COVID-19 pandemic
Identifying candidate drugs effective in the new coronavirus disease 2019 (Covid‐19) is crucial, pending a vaccine against SARS‐CoV2. We suggest the hypothesis that Cannabidiol (CBD),
Fighting the storm: novel anti- TNFα and anti-IL-6 C. sativa lines to tame cytokine storm in COVID-19
Acute inflammation and pathogenesis of SARS-CoV-2 infection: Cannabidiol as a potential anti-inflammatory treatment?
SARS-CoV2 induced respiratory distress: Can cannabinoids be added to anti-viral therapies to reduce lung inflammation?
In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues
Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures
Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer
ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma
Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells
Dramatic response to Laetrile and cannabidiol (CBD) oil in a patient with metastatic low grade serous ovarian carcinoma
Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells
Endocannabinoid System: A Fifty Year Trip – Raphael Mechoulam
Matching an effective cannabis strain extract for a specific subtype of cancer – David Meiri
Can cannabidiol inhibit angiogenesis in colon cancer?
Identifying the Cannabis Compounds that Kill Cancer
Dr David Allen, Cardiac & Trauma Surgeon-Retired / Cannabis Activist and Educator, USA
Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways
Prof. Raphael Mechoulam – Medical Cannabis – Complete Interview with Live Doctors
Inhibition of cervical cancer cell proliferation by cannabidiol
Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture
Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells
Dr David Allen the discovery of the Endocannabinoid System
Isolated cannabidiol from Cannabis sativa plant extracts inhibit growth and induce apoptosis in cervical cancer cells
The Scientist
Dr Sanjay Gupta: Weed – CNN Special Documentary
Cannabis Extract Treatment for Terminal Acute Lymphoblastic Leukemia with a Philadelphia Chromosome Mutation
Modulating the endocannabinoid system in human health and disease – successes and failures
Cannabidiol Science, For Doctors, For Patients
Id-1 is a Key Transcriptional Regulator of Glioblastoma Aggressiveness and a Novel Therapeutic Target
Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
anandamide autism bonni goldstein brain cancer breast cancer cancer cannabidiol Cannabinoid Hyperemesis Syndrome cannabinoids cbc cbd cbdv cbg cervical cancer cervical cancer Id-1 colon cancer colorectal cancer colorectal cancer id-1 covid ecs endocannabinoid system ependymoma epilepsy gastric cancer GDF15 glioblastoma glioma head and neck cancer Id-1 JNK1 JNK2 leukemia lung cancer lymphatic drainage opioids ovarian cancer ovarian cancer Id-1 pancreatic cancer physiological effects PPARγ prostate cancer raphael mechoulam self-renewal traumatic brain injury TRPV2