Cannabidiol on the Path from the Lab to the Cancer Patient: Opportunities and Challenges
Abstract Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent….
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Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment
Abstract Introduction: Glioblastoma (GBM) is the most common invasive brain tumor composed of diverse cell types with poor prognosis….
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Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes…
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Cannabidiol suppresses 3-dimensional ovarian cancer growth and may enhance potency of classic and epigenetic therapies
Over an extended kinetic, high and medium concentrations of one time CBD (CBDH) tended to stunt spheroid growth…
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Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins
Abstract Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of…
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Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
Abstract The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD),…
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Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma
Abstract Cannabidiol (CBD) has anti-tumorigenic activity. However, the anti-cancer effect of CBD on head and neck squamous cell…
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CBD as a Promising Anti-Cancer Drug
Abstract Recently, cannabinoids, such as cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), have been the subject of intensive research and…
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Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticles
In this work, we evaluated, for the first time, the antitumor effect of cannabidiol (CBD) as monotherapy and…