Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells
This research was done in vitro, results in vitro do not always carry over to human trials. Results…
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Isolated cannabidiol from Cannabis sativa plant extracts inhibit growth and induce apoptosis in cervical cancer cells
Abstract Cervical cancer remains a global health related issue among females of Sub-Saharan Africa, with over half a…
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Cannabis Extract Treatment for Terminal Acute Lymphoblastic Leukemia with a Philadelphia Chromosome Mutation
Abstract Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells and is typically well treated…
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Id-1 is a Key Transcriptional Regulator of Glioblastoma Aggressiveness and a Novel Therapeutic Target
Abstract Glioblastoma (GBM) is the most common form of primary adult brain tumors. A majority of GBMs grow…
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Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
Abstract The aggressive behavior of Glioblastoma multiforme (GBM) is mainly due to high invasiveness and proliferation rate as…
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Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
Abstract Colon cancer affects millions of individuals in Western countries. Cannabidiol, a safe and non-psychotropic ingredient of Cannabis sativa,…
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Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1
Although cannabinoids exhibit a broad variety of anticarcinogenic effects, their potential use in cancer therapy is limited by their psychoactive…
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Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
Abstract The cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor agonist Δ9-tetrahydrocannabinol (THC) has been shown to be…
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Id-1: Regulator of EGFR and VEGF and potential target for colorectal cancer therapy
This study revealed that Id-1, EGFR and VEGF took part in development and progression of colorectal carcinomas and…
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Overexpression of Id-1 protein is a marker in colorectal cancer progression
Abstract The inhibitor of differentiation/DNA binding 1 (Id-1), a negative regulator of basic helix-loop-helix transcription factors, plays an…