Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes…
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Cannabidiol suppresses 3-dimensional ovarian cancer growth and may enhance potency of classic and epigenetic therapies
Over an extended kinetic, high and medium concentrations of one time CBD (CBDH) tended to stunt spheroid growth…
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Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins
Abstract Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of…
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Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma
Abstract Cannabidiol (CBD) has anti-tumorigenic activity. However, the anti-cancer effect of CBD on head and neck squamous cell…
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CBD as a Promising Anti-Cancer Drug
Abstract Recently, cannabinoids, such as cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), have been the subject of intensive research and…
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Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticles
In this work, we evaluated, for the first time, the antitumor effect of cannabidiol (CBD) as monotherapy and…
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Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
Abstract Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The…
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Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures
Abstract Radiotherapy combined with chemotherapy is the major treatment modality for human glioblastoma multiforme (GBM). GBMs eventually relapse…
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Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer
Abstract According to recent studies, Cannabidiol (CBD), one of the main components of Cannabis sativa, has anticancer effects in…