Tag: cervical cancer Id-1

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Expression of the inhibitor of DNA-binding (ID)-1 protein as an angiogenic mediator in tumour advancement of uterine cervical cancers

Abstract [CONDENSED]

…the 36-month survival rate of patients with high ID-1 was poor (60%), whereas that of the patients with low ID-1 was significantly higher (83%). ID-1 correlated with microvessel counts in uterine cervical cancers. ID-1 expression also correlated significantly with histoscore. Therefore, ID-1 might work on tumour advancement through angiogenic activity and is considered to be a candidate for a prognostic indicator in uterine cervical cancers.

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Overexpression of Id-1 Protein Is a Marker for Unfavorable Prognosis in Early-Stage Cervical Cancer

Abstract [condensed]

We investigated the prognostic influence of Id-1 expression in 89 patients with cervical cancer. patients with strong or moderate expression of Id-1 had a significant shorter overall survival time and disease-free survival time compared with those with low or absent Id-1 expression. Id-1 expression is an independent prognostic marker in early-stage cervical cancer.

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