Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment
Abstract Introduction: Glioblastoma (GBM) is the most common invasive brain tumor composed of diverse cell types with poor prognosis….
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Cannabidiol suppresses 3-dimensional ovarian cancer growth and may enhance potency of classic and epigenetic therapies
Over an extended kinetic, high and medium concentrations of one time CBD (CBDH) tended to stunt spheroid growth…
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Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins
Abstract Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of…
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Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma
Abstract Cannabidiol (CBD) has anti-tumorigenic activity. However, the anti-cancer effect of CBD on head and neck squamous cell…
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CBD as a Promising Anti-Cancer Drug
Abstract Recently, cannabinoids, such as cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), have been the subject of intensive research and…
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Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticles
In this work, we evaluated, for the first time, the antitumor effect of cannabidiol (CBD) as monotherapy and…
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Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
Abstract Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The…
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The potential of cannabidiol in the COVID-19 pandemic
Identifying candidate drugs effective in the new coronavirus disease 2019 (Covid‐19) is crucial, pending a vaccine against SARS‐CoV2….
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Fighting the storm: novel anti- TNFα and anti-IL-6 C. sativa lines to tame cytokine storm in COVID-19
Overall, we are the first to show that application of C. sativa extracts profoundly decreases the level of…