Cannabidiol suppresses 3-dimensional ovarian cancer growth and may enhance potency of classic and epigenetic therapies
Over an extended kinetic, high and medium concentrations of one time CBD (CBDH) tended to stunt spheroid growth…
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Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins
Abstract Background:Â We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of…
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CBD as a Promising Anti-Cancer Drug
Abstract Recently, cannabinoids, such as cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), have been the subject of intensive research and…
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Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
Abstract Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The…
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Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures
Abstract Radiotherapy combined with chemotherapy is the major treatment modality for human glioblastoma multiforme (GBM). GBMs eventually relapse…
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Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer
Abstract According to recent studies, Cannabidiol (CBD), one of the main components of Cannabis sativa, has anticancer effects in…
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ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma
Abstract Glioblastoma is the most common primary brain tumor in adults. While the introduction of temozolomide chemotherapy has…
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Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells
Abstract The main chemical component of cannabis, cannabidiol (CBD), has been shown to have antitumor properties. The present…
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Dramatic response to Laetrile and cannabidiol (CBD) oil in a patient with metastatic low grade serous ovarian carcinoma
Highlights Keywords: Cannabidol, Laetrile, Low grade ovarian cancer, Complimentary alternative medicine Introduction Low grade serous ovarian cancer (LGSOC)…
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Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Abstract Glioblastoma multiforme (GBM) is the most common and aggressive form of primary malignant brain tumor in adults,…